PREVALENCE OF METHICILLIN-RESISTANT Staphylococcus aureus (MRSA) ISOLATED FROM DIFFERENT CLINICAL SAMPLES IN WESTERN REGIONAL HOSPITAL ,POKHARA 

Abstract

Staphylococcus aureus is one of common cause of Hospital acquired infection
and community acquired infection. Now days these organisms became resistant
towards variety of drugs. MRSA is a public health burden in developing
countries. This study was aimed to determine the prevalence and antibiotic
susceptibility pattern of S. aureus from clinical specimens (Blood, Urine, Sputum
and pus) in patients visiting Western Regional Hospital, Pokhara from 15th April
2010 to 15th February 2011.
This study was conducted in altogether 3269 samples. For isolation and
identification of MRSA culture and different biochemical tests were performed.
Out of 196 S. aureus isolated 107 were from pus, 54 were from Blood, 33 were
from Urine and 2 were from Sputum. Among 23.97% of MRSA more MRSA was
noticed in Female (25%)than Male (22.9%), However there is no significant
association between gender and MRSA(P≥ 0.05).
The prevalence of MRSA 23.9%. Hence, it was concluded that prevalence of
MRSA still emerging. Vancomycin was found to be most effective (100%)
against Methicillin-Resistant S. aureusfollowed by Ciprofloxacin 82.14%. so
vancomycin was found to be the drug of choice for the treatment of MRSA
infection.